About HDL DIRECT CHOLESTEROL (Liquid)
- Lipoproteins are spherical-shapedparticles that contain varying amounts of cholesterol, triglycerides,phospholipids and proteins. The relative amounts of the protein and lipidconstituents determine the density of the lipoprotein particles. The role ofhigh-density lipoprotein (HDL) particles in lipid metabolism is primarily theuptake and transport of cholesterol from peripheral tissue to the liver. Thisprocess is known as reverse cholesterol transport and has been proposed as acardio protective mechanism. Low HDL-C levels have repeatedly been associatedwith an increased risk of coronary heartdisease and coronary artery disease. Thus, the determination of serum HDLcholesterol has been recognized as a useful tool in identifying high-riskpatients.
Advanced Direct Enzymatic MeasurementThis reagent employs a direct enzymatic principle that allows HDL cholesterol measurement without precipitation steps, enhancing workflow simplicity and minimizing potential errors. Laboratories benefit from improved efficiency, as the method delivers quick and consistent results suitable for routine clinical use.
Instrument Compatibility and VersatilityHDL DIRECT CHOLESTEROL (Liquid) is compatible with a wide range of clinical chemistry analyzers, making it a versatile choice for laboratories of varying sizes. Its liquid form facilitates easy handling, ensuring smooth integration into automated systems for high-throughput operations.
Storage and Stability GuidelinesTo retain optimal reagent performance, HDL DIRECT CHOLESTEROL (Liquid) should be stored between 2C and 8C. Proper storage prevents degradation, ensuring consistent accuracy in cholesterol testing and long shelf life for laboratory stocks.
FAQs of HDL DIRECT CHOLESTEROL (Liquid):
Q: How is HDL DIRECT CHOLESTEROL (Liquid) used in clinical laboratories?
A: The reagent is utilized for the quantitative determination of HDL cholesterol in serum or plasma samples using clinical chemistry analyzers, providing accurate and efficient results for patient assessments.
Q: What is the principle behind this diagnostic reagent?
A: HDL DIRECT CHOLESTEROL (Liquid) works on a direct enzymatic method, which measures HDL cholesterol levels without requiring precipitation or separation steps, streamlining the analysis process.
Q: When should the reagent be stored at specific temperatures?
A: To maintain its stability and reliability, the reagent should always be stored at temperatures between 2C and 8C, both before and after opening, until its expiration date.
Q: Where is this reagent manufactured and exported from?
A: HDL DIRECT CHOLESTEROL (Liquid) is manufactured in India and exported internationally by a reputable supplier, ensuring high standards of quality and global availability.
Q: What are the benefits of the direct enzymatic method used?
A: This method improves accuracy and reduces testing time by eliminating precipitation and separation procedures, making the workflow more efficient for laboratories while minimizing operator error.
Q: How is the measurement carried out using this reagent?
A: The test is conducted through a colorimetric, end-point process, where the change in color intensity is directly proportional to the HDL cholesterol concentration in the sample.
Q: Can it be used with different clinical chemistry analyzers?
A: Yes, HDL DIRECT CHOLESTEROL (Liquid) is compatible with a wide variety of clinical chemistry analyzers, enabling flexible adoption across diagnostic laboratory setups.